Mountain and Lake Paradise with Our Boy Bob
from 06 August 2027 to 21 August 2027 · 15 nights
Salem, SC, US
- 1 dog
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Discover house sitting in Pickens
Stay in wonderful places by house sitting and caring for cute pets.
106 house sits in Pickens, SC, US
Looking for pet sitters in Pickens?
Lake House paradise…Lake Keowee South Carolina. You will want to come back.
from 21 December 2026 to 27 December 2026 · 6 nights
Salem, SC, US
- 1 dog
Spectacular lake front property; Very relaxing.
from 10 December 2026 to 20 December 2026 · 10 nights
Clemson, SC, US
- 2 dogs
Cozy home in Greenville, SC with a sweet Doberman and outdoor cat
from 20 November 2026 to 28 November 2026 · 8 nights
Greenville, SC, US
- 1 dog
- 1 cat
Bright, spacious home with high-tech amenities, screened porch and chefs kitchen
from 22 December 2026 to 27 December 2026 · 5 nights
Greenville, SC, US
- 2 cats
1 Week Stay in Greenville SC
from 10 January 2027 to 17 January 2027 · 7 nights
Greenville, SC, US
- 1 dog
- 1 cat
Modern Home Near Downtown Greenville
from 22 December 2026 to 31 December 2026 · 9 nights
Greenville, SC, US
- 2 cats
Newly Built Modern Farmhouse in Greenville, SC.
from 22 November 2026 to 27 November 2026 · 5 nights
Greenville, SC, US
- 2 dogs
Downtown Greenville Home
from 30 October 2026 to 02 November 2026 · 3 nights+ 1 more
Greenville, SC, US
- 3 dogs
Why you'll love pet and house sitting in Pickens, SC
Forget hotel roomsFrom home comforts to the calming company of pets, house sitting offers so much more.
It feels good to giveExplore new places while making a difference to the lives of pets and people along the way.
A new perspectiveYou don’t have to travel far. With pet and house sitting, you can find a world of adventures just around the corner.
A win-win without money
On house and pet sits, you’ll provide home and pet care in return for a place to stay on your travels. An annual plan unlocks unlimited access to sits, making it an affordable and fulfilling way to travel.
Find out more about memberships
“
I am so blessed to have this experience and to be able to have a companion by my side the entire time. I’m forever grateful for the opportunity TrustedHousesitters provides! This is truly life changing.
Adelia, sitter member from Bath, UK
Popular pet sitting and house sitting destinations
Feel safe, secure and supported
Read feedback from sittersWant to know if a house sit is right for you? Look for feedback previous sitters have left on the pet parent's listing.
Home & Contents PlanHouse sit in homes with peace of mind they’re covered at no extra cost to you or the pet parent.
24/7 Vet Advice LineWith a free direct line to a dedicated team of veterinary nurses, you can quickly clear up any pet queries.
Ready to start your Pickens house sitting adventure?
Join our worldwide community and start your membership today.
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Pickens house sitting FAQs
All that’s exchanged between our sitters and pet parents is trust - sitters get to stay in cool locations near and far, caring for pets with a place to stay in return. And with no money passing hands, we’re certain everybody’s here for the same reasons: their never-ending love for pets and travel.
With an annual sitter membership, animal lovers like you can explore the world and enjoy unique stays in exchange for pet care. Live like a local, care for adorable pets, and provide pet parents with peace of mind while they’re away. Apply for as many sits as you like and get ready for meaningful connections and unforgettable adventures.
Choose your membership plan and create a profile that stands out from the pack - include clear photos, relevant experience, and references (these don’t have to be from previous house sits). Next, set up a saved search to be the first to find out when house sitting opportunities in Pickens become available for your chosen dates. Once you’ve found the ideal sit, write a personalized message to the pet parents explaining why you're the perfect person for their furry friend! Find out more with 10 tips on how to become a house sitter.
Your number one priority when house sitting in Pickens will be taking care of the pets. Daily walks, mealtimes, and lots of cuddles will be top of the agenda as most house sits include a pet. Aside from this, house sitters in Pickens need to keep the home clean and tidy and send regular updates to the pet parents about their precious pet pals.
At TrustedHousesitters, our members are driven by a genuine love of pets, not money. They exchange loving pet care for a place to stay on their travels, gaining a wealth of experiences and memories to last a lifetime.